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6/30/2025 6:27:16 AM | Browse: 4 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 109105
Country United States
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Gut microbiome-specific nanoparticle-based therapeutics for liver diseases
Manuscript Source Invited Manuscript
All Author List Amit Khurana and Phillipp Hartmann
Funding Agency and Grant Number
Funding Agency Grant Number
University of California San Diego Altman Clinical and Translational Research Institute KL2TR001444
2022 Pinnacle Research Award in Liver Diseases from the American Association for the Study of Liver Diseases Foundation PNC22-159963
National Institutes of Health P30 DK120515
Corresponding Author Phillipp Hartmann, Assistant Professor, MD, Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States. phhartmann@health.ucsd.edu
Key Words Nanomedicine; Chronic liver diseases; Gut microbiome; Microbial metabolites; Precision medicine
Core Tip Chronic liver diseases are driven by metabolic, immune, and microbiome dysregulation. In this review, we detail recent advances in nanomedicine that enable tailored modulation of the gut microbiota, which can improve chronic liver diseases. Nanoparticles increase pharmacological effects and can reduce off-target effects. Further, artificial intelligence and machine learning can aid in production of precision nanomedicine.
Citation Khurana A, Hartmann P. Gut microbiome-specific nanoparticle-based therapeutics for liver diseases. World J Gastroenterol 2025; In press
Received
2025-04-29 03:00
Peer-Review Started
2025-04-29 03:01
To Make the First Decision
Return for Revision
2025-05-10 01:57
Revised
2025-05-29 15:48
Second Decision
2025-06-30 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-30 06:27
Articles in Press
2025-06-30 06:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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