Publication Name	World Journal of Clinical Oncology
Manuscript ID	109247
Country	Spain

Category	Oncology
Manuscript Type	Minireviews
Article Title	Radiotherapy treatment time delay evidence, part-I: Cervix, anal, prostate and head-and-neck cancer update
Manuscript Source	Invited Manuscript
All Author List	Jose Antonio González Ferreira, Castalia Fernandez, Daniela Gonsalves, Imanol Paguey and Felipe Couñago
Funding Agency and Grant Number
Corresponding Author	Jose Antonio González Ferreira, MD, Department of Radiation Oncology, Genesis Care-Spain, Américo Vespucio Street 31-33, Sevilla 41092, Spain. jose.gonzalez@genesiscare.es
Key Words	Radiotherapy; Overall treatment time; Delays; Loco-regional control; Survival; Cervix; Anal; Prostate; Head and neck cancer
Core Tip	Prolongation of overall treatment time (OTT) during radiotherapy significantly impacts loco-regional control and survival outcomes across several tumor types. This mini-review highlights strong evidence supporting the detrimental effect of OTT delays in head and neck and cervix cancers, with moderate evidence for prostate cancer and emerging concern in anal cancer. Recognizing the critical role of maintaining planned treatment schedules, we emphasize the need for proactive management of interruptions and suggest practical recommendations based on current evidence. Early identification and mitigation of treatment delays can substantially improve oncological outcomes across multiple malignancies.
Citation	González Ferreira JA, Fernandez C, Gonsalves D, Paguey I, Couñago F. Radiotherapy treatment time delay evidence, part-I: Cervix, anal, prostate and head-and-neck cancer update. World J Clin Oncol 2025; In press

Received	2025-05-06 02:15
Peer-Review Started	2025-05-06 02:15
To Make the First Decision
Return for Revision	2025-05-22 11:14
Revised	2025-06-04 18:43
Second Decision	2025-09-05 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-05 10:34
Articles in Press	2025-09-05 10:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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