| Category |
Anesthesiology |
| Manuscript Type |
Prospective Study |
| Article Title |
Nottingham Hip Fracture Score and Acute Physiology and Chronic Health Evaluation-II: Predicting 30-day mortality in elderly hip fracture
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Deb Sanjay Nag, Shailendra Prasad, Seelora Sahu, Jayanta Kumar Laik, Amlan Swain, Rishi Anand, Swati Saroha, Pratap Rudra Mahanty, Himanshu Kumar and Walmik Mistari |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Deb Sanjay Nag, Department of Anaesthesiology, Tata Main Hospital, C Road West, Northern Town, Bistupur, Jamshedpur 831001, Jharkhand, India. ds.nag@tatasteel.com |
| Key Words |
Acute Physiology and Chronic Health Evaluation-II; Hip fractures; Scoring methods; Mortality; Geriatrics; Outcome assessment; Receiver operating characteristic curve |
| Core Tip |
This prospective observational study at Tata Main Hospital in Jamshedpur, India, evaluated the Nottingham Hip Fracture Score (NHFS) and Acute Physiology and Chronic Health Evaluation (APACHE)-II score for predicting 30-day mortality in 182 geriatric patients with hip fracture (≥ 60 years). The study assessed the primary (mortality prediction) and secondary objectives, including the requirement for ventilator/ionotropic support and monitoring for acute kidney injury and other complications. Preoperatively, the NHFS and APACHE-II scores were calculated, and patients were followed up for a minimum of 30 days post-surgery. Statistical analyses included receiver operating characteristic curves, area under the curve (AUC), sensitivity, specificity, and P value using Statistica. Results indicated that NHFS showed moderate predictive accuracy (AUC = 0.709, P = 0.006), whereas APACHE-II demonstrated excellent predictive ability (AUC = 0.904, P < 0.001). Significant predictors of mortality included the APACHE-II score, NHFS, mean arterial pressure, pH, respiratory rate, and serum creatinine levels. Although age and gender showed notable trends, they were not statistically significant. The findings indicate that the APACHE-II score is a strong predictor of 30-day mortality following hip fracture surgery, highlighting the importance of incorporating multiple factors for effective prediction. |
| Citation |
Nag DS, Prasad S, Sahu S, Laik JK, Swain A, Anand R, Saroha S, Mahanty PR, Kumar H, Mistari W. Nottingham Hip Fracture Score and Acute Physiology and Chronic Health Evaluation-II: Predicting 30-day mortality in elderly hip fracture. World J Methodol 2025; In press |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
