Publication Name	World Journal of Diabetes
Manuscript ID	109553
Country	China

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Basic Study
Article Title	Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells
Manuscript Source	Unsolicited Manuscript
All Author List	Yan Guo, Xin-Rou Yu, Hao-Di Gu, Yu-Jie Wang, Zhen-Gang Yang, Ju-Fang Chi, Liu-Ping Zhang and Lin Hui
Funding Agency and Grant Number	Funding Agency Grant Number Medical Health Science and Technology Project of Zhejiang Provincial 2025KY1721 and 2022KY1292 Science and Technology Projects of Shaoxing City 2022KY104
Corresponding Author	Lin Hui, MD, PhD, Department of Cardiology, The Affiliated Lihuili Hospital of Ningbo University, No. 57 Xingning Road, Yinzhou District, Ningbo 315211, Zhejiang Province, China. 122525790@qq.com
Key Words	Diabetic cardiomyopathy; Microvascular dysfunction; Farrerol; MiR-29b-3p; SIRT1
Core Tip	This study was the first to identify the miR-29b-3p/SIRT1 axis as a critical mechanism underlying the attenuation of endothelial ferroptosis and microvascular dysfunction of farrerol (FA) in diabetic cardiomyopathy (DCM). These results highlight the translational potential of targeting miR-29b-3p or administering FA for the treatment of DCM.
Citation	Guo Y, Yu XR, Gu HD, Wang YJ, Yang ZG, Chi JF, Zhang LP, Hui L. Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells. World J Diabetes 2025; In press

Received	2025-05-16 10:27
Peer-Review Started	2025-05-20 00:11
To Make the First Decision
Return for Revision	2025-06-04 03:30
Revised	2025-06-16 08:53
Second Decision	2025-08-08 09:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-15 10:46
Articles in Press	2025-08-15 10:46
Publication Fee Transferred	2025-06-20 10:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com