Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	109579
Country	Tunisia

Category	Oncology
Manuscript Type	Randomized Controlled Trial
Article Title	Diet and physical activity in colorectal cancer patients: A research protocol of a randomized controlled study
Manuscript Source	Unsolicited Manuscript
All Author List	Ali Mohamed Aboturkia, Wala Ben Kridis, Mukhtar Omer Aqoup, Munir Omer Abdoalmola, Suhil Ben Ali and Afef Khanfir
Funding Agency and Grant Number
Corresponding Author	Wala Ben Kridis, Academic Editor, Associate Professor, MD, PhD, Department of Oncology, Habib Bourguiba university hospital, University of Sfax, Sfax, Tunisia, Department of Oncology, Habib Bourguiba Hospital Sfax 3029, Tunisia. walabenkridis@yahoo.fr., Sfax 3008, Tunisia. walabenkridis@yahoo.fr
Key Words	Colorectal cancer; Diet; Physical activity; Behavioral targets; Overall survival; Disease free survival
Core Tip	What is already known on this topic: The number of colorectal cancer (CRC) survivors is steadily rising, creating an urgent demand for effective and sustainable post-treatment care strategies. Although lifestyle factors such as diet and physical activity (PA) are known to influence cancer outcomes, there is a notable lack of evidence-based, structured programs to guide survivors in adopting and maintaining these changes—especially in African and resource-limited settings. What this study adds: This study evaluates the impact of two targeted behavioral interventions—increasing PA and reducing red and processed meat intake—on long-term outcomes in CRC survivors. It is among the first randomized controlled trials in Africa to assess the combined and independent effects of these lifestyle changes on survival and quality of life. How this study might affect research, practice, or policy: Our findings could transform survivorship care by providing region-specific evidence to support the integration of lifestyle counseling into routine oncology practice. This program may serve as a model for preventive care that improves both disease-free and overall survival while influencing future clinical guidelines and public health policy.
Citation	Aboturkia AM, Ben Kridis W, Aqoup MO, Abdoalmola MO, Ben Ali S, Khanfir A. Diet and physical activity in colorectal cancer patients: A research protocol of a randomized controlled study. World J Gastrointest Oncol 2025; In press

Received	2025-05-15 05:41
Peer-Review Started	2025-05-15 05:41
To Make the First Decision
Return for Revision	2025-06-05 08:18
Revised	2025-06-05 15:47
Second Decision	2025-07-09 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-09 06:43
Articles in Press	2025-07-09 06:43
Publication Fee Transferred	2025-06-20 21:20
Edit the Manuscript by Language Editor	2025-07-11 18:27
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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