Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	109777
Country	China

Category	Oncology
Manuscript Type	Case Control Study
Article Title	Untargeted metabolomics analysis of metabolite changes in gastric cancer patients from plateau regions
Manuscript Source	Unsolicited Manuscript
All Author List	Ling-Hong Zhu, Zhao-Xin Jin, Yan-Qing Ma, Xiao Feng, Cai-Hong Ci, Yun-Song Zhou, Qiao-Ling Gu, Yong-Mei Lan and Zi-Long Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Gansu Provincial Natural Science Foundation Project 23JRRA725 Postgraduate Research Innovation Project of Northwest Minzu University in 2025 31920250001-38 2024 Qinghai Province's "Kunlun Talent High-end Innovative and Entrepreneurial Talent Project" Cultivates Top Talents Project QHKLYC-GDCXCY-2024-155
Corresponding Author	Yong-Mei Lan, Department of Gastrointestinology, Northwest Minzu University, Northwest Minzu University, Lanzhou, Gansu, Lanzhou 730030, Gansu Province, China. xbmdlym@sina.com
Key Words	Plateau regions; Gastric cancer; Untargeted metabolomics; Metabolites; Metabolic pathways
Core Tip	This study reveals distinct alterations in gut microbial metabolites and metabolic pathways in gastric cancer patients from high-altitude regions, highlighting potential metabolic biomarkers and pathways (e.g., purine, biotin, and amino acid metabolism) that may inform early diagnosis or targeted therapies in this unique population.
Citation	Zhu L, Jin Z, Ma YQ, Feng X, Ci CH, Zhou YS, Gu QL, Lan YM, Zhang ZL. Untargeted metabolomics analysis of metabolite changes in gastric cancer patients from plateau regions. World J Gastrointest Oncol 2025; In press

Received	2025-05-27 08:07
Peer-Review Started	2025-05-27 08:07
To Make the First Decision
Return for Revision	2025-06-03 02:15
Revised	2025-06-09 03:18
Second Decision	2025-08-19 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-19 06:38
Articles in Press	2025-08-19 06:38
Publication Fee Transferred	2025-06-11 01:48
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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