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Articles in Press
8/20/2025 11:14:25 AM | Browse: 116 | Download: 0
| Category |
Critical Care Medicine |
| Manuscript Type |
Case Report |
| Article Title |
Thrombotic storm presenting with synchronous myocardial infarction, stroke and bowel ischaemia: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Jian Chan, Timothy Xin Zhong Tan, R Ponampalam and Arjun Thompson |
| Funding Agency and Grant Number |
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| Corresponding Author |
Wen-Jian Chan, Department of Emergency Medicine, SingHealth, SINGAPORE GENERAL HOSPITAL Outram Road Singapore 169608, Singapore 169608, Singapore. chan.wenjian@gmail.com |
| Key Words |
Thrombosis; Stroke; Acute myocardial infarct; Ischaemic bowel; Case report |
| Core Tip |
This case describes the first known instance of simultaneous myocardial infarction, stroke, and bowel infarction, likely due to a thrombotic crisis. Synchronous cardiocerebral infarcts are rare (0.009%–0.29%) and typically affect older males. Etiology remains unclear but may involve cardiogenic shock reducing cerebral perfusion. Management requires a multidisciplinary approach. If within the thrombolysis window (4.5 hours), IV recombinant tissue plasminogen activator (0.9 mg/kg) should be given first, followed by coronary intervention. Outside this window, treatment prioritization depends on hemodynamic stability—cardiac intervention for shock, stroke management otherwise. Post-acute care involves high-dose statins if atherosclerosis is suspected and close monitoring in a high-acuity setting. |
| Citation |
Chan WJ, Tan TXZ, Ponampalam R, Thompson A. Thrombotic storm presenting with synchronous myocardial infarction, stroke and bowel ischaemia: A case report. World J Crit Care Med 2025; 14(4): 109786 |
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Received |
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2025-05-22 06:58 |
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Peer-Review Started |
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2025-05-22 06:58 |
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First Decision by Editorial Office Director |
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2025-06-12 01:33 |
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Return for Revision |
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2025-06-12 01:33 |
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Revised |
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2025-06-17 09:01 |
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Publication Fee Transferred |
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2025-06-27 02:55 |
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Second Decision by Editor |
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2025-08-20 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-20 11:14 |
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Articles in Press |
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2025-08-20 11:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-13 06:59 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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