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Articles in Press
8/5/2025 6:04:33 AM | Browse: 140 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Risk factors and long-term prognosis for colorectal strictures in ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Pei Shao, Tao-Tao Han, Hong Lv, Sun-Ting Yang, Qing-Li Zhu, Ji Li and Jing-Nan Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82270567 |
| Central High-Level Hospital Clinical Research Project of Peking Union Medical College Hospital |
No. 2022-PUMCH-B-022 |
| Central High-Level Hospital Clinical Research Project of Peking Union Medical College Hospital |
No. 2022-PUMCH-C-055 |
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| Corresponding Author |
Jing-Nan Li, MD, PhD, Professor, Department of Gastroenterology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. jnli2020@126.com |
| Key Words |
Inflammatory bowel disease; Ulcerative colitis; Stricture; Prognosis; Risk factors |
| Core Tip |
Limited studies have focused on the long-term clinical outcomes and risk factors associated with strictures in ulcerative colitis (UC). This cohort study analyzed 938 UC patients with a median follow-up time of 8.70 years. The incidence of UC strictures was 12.4% with 8.6% confirmed as malignant. UC patients with strictures had poor treatment efficacy and higher risks of surgery, intestinal complications and colorectal cancer. Age ≥ 40 years at diagnosis and extraintestinal manifestations were risk factors for stricture formation, while vedolizumab use was protective. Sensitivity analysis, excluding malignant strictures showed consistent findings. |
| Citation |
Shao YP, Han TT, Lv H, Yang ST, Zhu QL, Li J, Li JN. Risk factors and long-term prognosis for colorectal strictures in ulcerative colitis. World J Gastroenterol 2025; 31(33): 109938 |
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Received |
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2025-05-26 03:03 |
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Peer-Review Started |
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2025-05-26 03:03 |
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First Decision by Editorial Office Director |
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2025-06-25 09:40 |
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Return for Revision |
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2025-06-25 09:40 |
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Revised |
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2025-07-08 08:41 |
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Publication Fee Transferred |
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2025-07-10 08:43 |
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Second Decision by Editor |
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2025-08-05 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-05 06:04 |
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Articles in Press |
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2025-08-05 06:04 |
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Edit the Manuscript by Language Editor |
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2025-08-11 05:33 |
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Typeset the Manuscript |
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2025-08-25 00:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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