Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109999
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Shock index and early warning score in liver cancer rupture shock
Manuscript Source	Unsolicited Manuscript
All Author List	Ji-Fen Ma, Li Jin, Ling Sha, Hong-Fang Li, Xiang-Yun Qian and Hai-Yan Wang
Funding Agency and Grant Number	Funding Agency Grant Number Clinical Medicine Special Research Fund Project of Nantong University 2024HZ001 and 2022HY009
Corresponding Author	Xiang-Yun Qian, Dean, Department of Emergency, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, No. 60 Qingnian Middle Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. qxy3066@163.com
Key Words	Primary liver cancer; Rupture hemorrhage; Shock index; Early warning score system; Complications
Core Tip	This study demonstrated that combining the shock index (SI, heart rate/systolic blood pressure ratio) with the early warning score (EWS) significantly improves outcomes in primary liver cancer rupture hemorrhage. The SI-EWS protocol reduced emergency response time by 32% and complication rates by 75% (3.39% vs 13.56%), and increased patient satisfaction to 94.92%. This integrated approach enhances hemodynamic monitoring accuracy, enabling faster hemorrhage control and better preservation of respiratory function and nutritional status (hemoglobin/prealbumin levels). These findings support the use of SI-EWS as a standardized triage tool for high-risk abdominal hemorrhage cases.
Citation	Ma JF, Jin L, Sha L, Li HF, Qian XY, Wang HY. Shock index and early warning score in liver cancer rupture shock. World J Gastrointest Surg 2025; In press

Received	2025-07-01 08:57
Peer-Review Started	2025-07-01 08:57
To Make the First Decision
Return for Revision	2025-07-21 08:15
Revised	2025-08-01 13:44
Second Decision	2025-08-18 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-18 06:18
Articles in Press	2025-08-18 06:18
Publication Fee Transferred	2025-08-04 15:40
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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