Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	110203
Country	Peru

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Rectal neuroendocrine tumors in a Latin American population: Insights from a Peruvian national cancer institute
Manuscript Source	Invited Manuscript
All Author List	Wagner Eduardo Cruz-Diaz, Angela Leonardo, Alexandra Saavedra, Victor Paitan, Juan Haro-Varas, Raul Mantilla, Jackeline Macetas, Eder Veramendi, Cristian Pacheco, Mónica Calderón, Tatiana Vidaurre and Victor Castro-Oliden
Funding Agency and Grant Number
Corresponding Author	Wagner Eduardo Cruz-Diaz, MD, Department of Medical Oncology, Instituto Nacional de Enfermedades Neoplásicas, Avenida Angamos Este 2520, Surquillo, Lima 15038, Peru. wagner.cruz@upch.pe
Key Words	Rectal neoplasms; Neuroendocrine tumors; Survival analysis; Retrospective studies; Treatment outcome
Core Tip	This retrospective study encompassed the largest known Peruvian patients with well-differentiated rectal neuroendocrine tumors. With a median overall survival of 76 months and a 5-year survival rate of 60.6%, outcomes were significantly affected by tumor size, grade, and nodal status. Grade 2 tumors, lesions > 20 mm, and nodal involvement were linked to poorer survival. These findings provide important regional data and support the integration of these factors into risk-stratification strategies for rectal neuroendocrine tumors in Perú.
Citation	Cruz-Diaz WE, Leonardo A, Saavedra A, Paitan V, Haro-Varas J, Mantilla R, Macetas J, Veramendi E, Pacheco C, Calderón M, Vidaurre T, Castro-Oliden V. Rectal neuroendocrine tumors in a Latin American population: Insights from a Peruvian national cancer institute. World J Gastrointest Oncol 2025; In press

Received	2025-06-04 01:35
Peer-Review Started	2025-06-04 01:35
To Make the First Decision
Return for Revision	2025-07-03 14:19
Revised	2025-07-17 07:01
Second Decision	2025-09-08 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-08 08:11
Articles in Press	2025-09-08 08:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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