Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	110243
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Gender, racial, and stage-specific trends in esophageal cancer: Insights from longitudinal population data
Manuscript Source	Invited Manuscript
All Author List	Silpa Choday, Anthony Yeung, Paul Kang, Tina Younger and Wael Youssef
Funding Agency and Grant Number
Corresponding Author	Silpa Choday, MD, Department of Internal Medicine, Creighton University School of Medicine, 3110 N Central Avenue, Phoenix, AZ 85012, United States. ushilpa19@gmail.com
Key Words	Esophageal cancer; Incidence; Mortality; Surveillance, Epidemiology, and End Results; Epidemiology
Core Tip	This population-based study uses Surveillance, Epidemiology, and End Results data (2004-2021) to assess trends in esophageal cancer incidence and mortality by demographic and clinical characteristics. While overall incidence is declining – particularly among males and non-Hispanic (NH) Black individuals – mortality remains disproportionately high in older adults, males, and those with distant-stage disease. Notably, NH Whites show a concerning upward trend in mortality. These findings highlight persistent disparities and underscore the need for targeted prevention, early detection, and improved treatment strategies.
Citation	Choday S, Yeung A, Kang P, Younger T, Youssef W. Gender, racial, and stage-specific trends in esophageal cancer: Insights from longitudinal population data. World J Gastrointest Pathophysiol 2025; In press

Received	2025-06-03 08:36
Peer-Review Started	2025-06-03 08:37
To Make the First Decision
Return for Revision	2025-06-30 06:53
Revised	2025-07-17 02:36
Second Decision	2025-11-25 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-26 00:47
Articles in Press	2025-11-26 00:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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