Publication Name	World Journal of Hepatology
Manuscript ID	110312
Country	Chile

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty
Manuscript Source	Unsolicited Manuscript
All Author List	Javier Delgado, Marcelo Fuentes, Daniela Simian, Jaime Poniachik and Álvaro Urzúa
Funding Agency and Grant Number
Corresponding Author	Álvaro Urzúa, MD, Division of Gastroenterology, Department of Medicine, Hospital Clínico Universidad de Chile, Dr. Carlos Lorca Tobar 999, Independencia, Santiago 8380456, Región Metropolitana, Chile. aurzuam@hcuch.cl
Key Words	Autoimmune hepatitis; Elderly; Diagnosis; Steroids; Fibrosis
Core Tip	This study highlights age-related differences in autoimmune hepatitis (AIH) presentation. Patients diagnosed after 60 years of age showed milder biochemical abnormalities but more advanced fibrosis and ascites at diagnosis. Despite receiving lower corticosteroid doses, their treatment response was comparable to younger patients. These findings suggest that AIH in older adults may represent a distinct clinical phenotype with important diagnostic and therapeutic implications.
Citation	Delgado J, Fuentes M, Simian D, Poniachik J, Urzúa Á. Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty. World J Hepatol 2025; In press

Received	2025-06-12 08:39
Peer-Review Started	2025-06-12 08:39
To Make the First Decision
Return for Revision	2025-06-18 07:11
Revised	2025-07-01 17:10
Second Decision	2025-11-17 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-17 08:54
Articles in Press	2025-11-17 08:54
Publication Fee Transferred	2025-10-29 12:43
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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