Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	110850
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Gyrus-like endoscopic changes in autoimmune gastritis with past Helicobacter pylori infection: Two case reports and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Chuan-Chuan Tan, Xue-Li Shangguan, Xiao-Ming Lei, Fang-Fang Deng, Yang-Peng Wu and Guo-Min Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) No. 81973920
Corresponding Author	Guo-Min Zhang, PhD, Professor, School of Integrated Chinese and Western Medicine, Hunan University of Traditional Chinese Medicine, No. 300 Xueshi Road, Changsha 410208, Hunan Province, China. 003334@hnucm.edu.cn
Key Words	Autoimmune gastritis; Atrophic gastritis; Past Helicobacter pylori infection; Gastric autoimmunity; Gyrus-like changes; Reverse atrophy; Endoscopic identification; Case report
Core Tip	We present two patients diagnosed with autoimmune gastritis (AIG) after past Helicobacter pylori infection. In both, the reverse atrophy characteristic of AIG was absent. We identified gyrus-like changes, characterized by mildly elevated mucosa between deep fissures, as a novel endoscopic feature. Histology confirmed the early pathology of AIG in these areas. This previously unrecognized endoscopic pattern offers a valuable clue of detecting AIG in patients with past Helicobacter pylori infection that may facilitate the early recognition and management of this condition
Citation	Tan CC, Shangguan XL, Lei XM, Deng FF, Wu YP, Zhang GM. Gyrus-like endoscopic changes in autoimmune gastritis with past Helicobacter pylori infection: Two case reports and review of literature. World J Gastrointest Endosc 2025; In press

Received	2025-06-17 07:32
Peer-Review Started	2025-06-17 07:32
To Make the First Decision
Return for Revision	2025-06-28 17:53
Revised	2025-07-11 02:35
Second Decision	2025-08-19 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-19 09:33
Articles in Press	2025-08-19 09:33
Publication Fee Transferred	2025-07-17 14:06
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Typeset the Manuscript

ISSN	1948-5190 (online)
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