Publication Name	World Journal of Psychiatry
Manuscript ID	110875
Country	China

Category	Psychiatry
Manuscript Type	Retrospective Study
Article Title	Analysis the incidence and related risk factors of depression in patients with esophageal cancer combined with bone metastasis
Manuscript Source	Unsolicited Manuscript
All Author List	Hao-Jie Shi, Shi-Chao Huang and Bing-Wu Wang
Funding Agency and Grant Number
Corresponding Author	Shi-Chao Huang, Chief Physician, Department of Orthopedics, People’s Hospital of Tongshan District, No. 267 Huaihai West Road, Quanshan District, Xuzhou 221100, Jiangsu Province, China. hxx20180817@163.com
Key Words	Esophageal cancer; Bone metastasis; Depression; Risk factors; Esophageal cancer; Bone metastasis
Core Tip	This retrospective study recruited 100 patients with esophageal cancer and bone metastasis, finding 42% had depression (assessed via Beck Depression Inventory-II). Multivariate logistic regression identified five independent risk factors: low monthly per capital household income [odds ratio (OR) = 2.66], low education (OR = 2.46), low social support (OR = 5.10), sleep disorders (OR = 2.79), and elevated high-sensitivity C-reactive protein (OR = 1.31 per unit increase). Targeted interventions for these factors may lower depression risk in this population.
Citation	Shi HJ, Huang SC, Wang BW. Analysis the incidence and related risk factors of depression in patients with esophageal cancer combined with bone metastasis. World J Psychiatry 2025; In press

Received	2025-07-15 09:28
Peer-Review Started	2025-07-15 09:28
To Make the First Decision
Return for Revision	2025-08-06 08:39
Revised	2025-08-15 14:07
Second Decision	2025-10-21 02:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-21 08:43
Articles in Press	2025-10-21 08:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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