Publication Name	World Journal of Hepatology
Manuscript ID	110931
Country	Spain

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	De novo arthropathy following glucocorticoid treatment for severe alcohol-associated hepatitis: Five case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Queralt Herms, Sonia Torres, Patrick S Kamath, Jordi Gratacós-Ginès and Elisa Pose
Funding Agency and Grant Number	Funding Agency Grant Number Instituto de Salud Carlos III PI22/00910
Corresponding Author	Jordi Gratacós-Ginès, MD, PhD, Liver Unit, Hospital Clínic de Barcelona, Villarroel 170, Barcelona 08036, Catalonia, Spain. jgrata@clinic.cat
Key Words	Corticosteroids; Alcohol-related; Arthralgia; Withdrawal syndrome; Cirrhosis; Joints; Case report
Core Tip	Despite most adverse events following glucocorticoid (GC) administration for severe alcohol-associated hepatitis (SAH) are well-known, joint symptoms are overlooked and not mentioned in hepatology literature. We report a series of five patients, selected from a prospective cohort of patients with biopsy-proven SAH, who developed joint symptoms following GC cessation. Although the final diagnosis varied among patients, the emergence of joint symptoms after GC therapy for SAH represents a novel and noteworthy observation for clinicians managing these cases. In this report we hypothesize that some patients suffered from GC withdrawal syndrome, and we describe the therapeutic approach used.
Citation	Herms Q, Torres S, Kamath PS, Gratacós-Ginès J, Pose E. De novo arthropathy following glucocorticoid treatment for severe alcohol-associated hepatitis: Five case reports. World J Hepatol 2025; In press

Received	2025-06-19 06:47
Peer-Review Started	2025-06-19 06:47
To Make the First Decision
Return for Revision	2025-07-17 10:21
Revised	2025-07-21 12:52
Second Decision	2025-11-17 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-17 09:06
Articles in Press	2025-11-17 09:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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