BPG is committed to discovery and dissemination of knowledge
Articles in Press
10/17/2025 2:00:26 AM | Browse: 173 | Download: 21
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Associations of clinical indexes and prognosis with gut-vascular barrier damage in patients with intestinal obstruction
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hu-Fei Zhang, Yi Guo, Xiao-Jun Chen, Yi-Nan Zhang, Hui Peng, Zi-Meng Liu and Xu-Yu Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82072204 |
| National Natural Science Foundation of China |
81701874 |
| Natural Science Foundation of Guangdong Province, China |
2021A1515010990 |
| Natural Science Foundation of Guangdong Province, China |
2025A1515012493 |
|
| Corresponding Author |
Xu-Yu Zhang, MD, PhD, Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No.58, Zhongshan 2th Road, Guangzhou 510080, Guangdong Province, China. zhangxuy@mail.sysu.edu.cn |
| Key Words |
Intestinal obstruction; Gut-vascular barrier; PV1; Infection; Organ injury; Clinical prognosis |
| Core Tip |
This study reveals that intestinal obstruction (IO) leads to gut-vascular barrier (GVB) damage, with PV1 expression positively correlating with infection, liver/kidney injury, and adverse outcomes. GVB impairment may contribute to IO pathogenesis, highlighting PV1 as a potential prognostic biomarker. |
| Citation |
Zhang HF, Guo Y, Chen XJ, Zhang YN, Peng H, Liu ZM, Zhang XY. Associations of clinical indexes and prognosis with gut-vascular barrier damage in patients with intestinal obstruction. World J Gastrointest Surg 2025; 17(12): 111041 |
 |
Received |
|
2025-07-29 08:46 |
|
Peer-Review Started |
|
2025-07-29 08:46 |
|
First Decision by Editorial Office Director |
|
2025-08-11 03:34 |
|
Return for Revision |
|
2025-08-11 03:34 |
|
Revised |
|
2025-09-02 09:36 |
|
Publication Fee Transferred |
|
2025-09-03 08:44 |
|
Second Decision by Editor |
|
2025-10-16 02:53 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-10-17 02:00 |
|
Articles in Press |
|
2025-10-17 02:00 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-12-15 02:50 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
