Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	111107
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Endoscopic biliary drainage with multi-hole self-expandable metallic stent during neoadjuvant chemoradiotherapy in pancreatic cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Shohei Asada, Koh Kitagawa, Junichi Hanatani, Yuki Motokawa, Yui Osaki, Tomihiro Iwata, Kosuke Kaji, Akira Mitoro, Minako Nagai, Hitoshi Yoshiji and Masayuki Sho
Funding Agency and Grant Number
Corresponding Author	Koh Kitagawa, MD, PhD, Department of Gastroenterology, Nara Medical University, 840 Shijou-cho, Kashihara, Japan 634-8522, Kashihara 634-8522, Nara, Japan. kitagawa@naramed-u.ac.jp
Key Words	Malignant biliary obstruction; Multi-hole self-expandable metallic stent; Neoadjuvant therapy; Neoadjuvant chemoradiotherapy; Pancreatic cancer
Core Tip	We investigated the usefulness of a novel multi-hole self-expandable metallic stent (MH-SEMS) for preoperative biliary drainage during neoadjuvant chemoradiotherapy (NACRT) in patients with pancreatic cancer (PC). We included 14 patients who underwent surgery following biliary drainage using MH-SEMS. Clinical and technical success were achieved in all patients. The median interval between stent placement and surgery was 105 days. Only one patient (7.1%) experienced recurrent biliary obstruction caused by sludge. MH-SEMS placement is a potentially effective treatment option for preoperative biliary drainage in patients with PC undergoing NACRT.
Citation	Asada S, Kitagawa K, Hanatani J, Motokawa Y, Osaki Y, Iwata T, Kaji K, Mitoro A, Nagai M, Yoshiji H, Sho M. Endoscopic biliary drainage with multi-hole self-expandable metallic stent during neoadjuvant chemoradiotherapy in pancreatic cancer. World J Gastrointest Endosc 2025; In press

Received	2025-06-24 09:12
Peer-Review Started	2025-06-24 09:13
To Make the First Decision
Return for Revision	2025-07-30 08:38
Revised	2025-08-10 23:31
Second Decision	2025-09-16 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-16 04:03
Articles in Press	2025-09-16 04:03
Publication Fee Transferred
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Typeset the Manuscript

ISSN	1948-5190 (online)
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