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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 111423
Country India
Category Pediatrics
Manuscript Type Case Control Study
Article Title Maternal and neonatal determinants of newborn sepsis: A case-control study in resource-limited settings
Manuscript Source Invited Manuscript
All Author List Mohd Asif Qureshi, Mangla Sood, Pratima Thakur and Ishaan Sood
Funding Agency and Grant Number
Corresponding Author Mangla Sood, MD, Professor, Department of Pediatrics, Indira Gandhi Medical College, Shimla Himachal Pradesh, Shimla 171001, Himachal Pradesh, India. drmanglasood@gmail.com
Key Words Infant; Low birth weight; Newborn; Neonatal sepsis; Noninvasive ventilation; Sepsis; Risk factors
Core Tip Neonatal sepsis in our study was strongly associated with several modifiable maternal and intrapartum factors namely insufficient antenatal visits, prolonged labor or membrane rupture, forceps delivery, non-sterile vaginal examinations, and maternal urinary tract infections. Compounded by neonatal vulnerabilities including prematurity, very low birth weight, small-for-gestational-age, birth asphyxia, advanced respiratory support need, prolonged newborn intensive care unit (NICU) stays, the latter reflecting greater exposure to nosocomial pathogens. Targeted, tiered interventions spanning antenatal care through delivery and the NICU, emphasizing risk stratification, aseptic practices, early surveillance and timely prophylaxis can sharply reduce sepsis rates and enhance newborn survival.
Citation Qureshi MA, Sood M, Thakur P, Sood I. Maternal and neonatal determinants of newborn sepsis: A case-control study in resource-limited settings. World J Clin Pediatr 2025; In press
Received
2025-07-01 02:25
Peer-Review Started
2025-07-01 02:25
To Make the First Decision
Return for Revision
2025-07-08 08:20
Revised
2025-07-09 14:47
Second Decision
2025-10-20 02:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-21 03:18
Articles in Press
2025-10-21 03:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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