Publication Name	World Journal of Gastroenterology
Manuscript ID	111494
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Repeat ablation and single-session ablation in patients with multiple colorectal cancer liver metastases after chemotherapy failure
Manuscript Source	Unsolicited Manuscript
All Author List	Si-Qi Gao, Bo-Wen Zhang, Qi-Yu Zhao and Tian-An Jiang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82027803 Key Research and Development Project of Zhejiang Province 2024C03092 National Natural Science Foundation of China 81971623
Corresponding Author	Tian-An Jiang, Professor, Senior Researcher, Department of Ultrasound, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. tiananjiang@zju.edu.cn
Key Words	Colorectal liver metastases; Radiofrequency ablation; Repeat ablation; Refractory; Long-term survival; Chemotherapy failure
Core Tip	This is a retrospective study to investigate long-term survival and factors affecting outcomes of radiofrequency ablation in patients with multiple refractory colorectal liver metastases after systemic chemotherapy failure. No significant differences emerged in overall survival or progression-free survival when comparing single-session with repeat ablation. Nevertheless, supplemental or additional ablation sessions appeared to improve the likelihood of patients attaining a tumor-free status, suggesting a potential benefit in refractory colorectal liver metastases.
Citation	Gao SQ, Zhang BW, Zhao QY, Jiang TA. Repeat ablation and single-session ablation in patients with multiple colorectal cancer liver metastases after chemotherapy failure. World J Gastroenterol 2025; In press

Received	2025-07-02 06:22
Peer-Review Started	2025-07-02 06:22
To Make the First Decision
Return for Revision	2025-08-11 07:28
Revised	2025-08-24 15:59
Second Decision	2025-10-21 02:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-21 06:10
Articles in Press	2025-10-21 06:10
Publication Fee Transferred	2025-08-25 03:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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