Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	111550
Country	China

Category	Cell Biology
Manuscript Type	Review
Article Title	Roles of chemokines in pancreatitis: A review
Manuscript Source	Unsolicited Manuscript
All Author List	Wei-Fang Ni and Chao-Chao Qin
Funding Agency and Grant Number	Funding Agency Grant Number Sichuan Provincial Geriatric Health Development Center and the Sichuan Gerontological Society 24SCLN0138
Corresponding Author	Chao-Chao Qin, MD, PhD, Oncology Internal Medicine Treatment Unit, Guangyuan Traditional Chinese Medicine Hospital Affiliated to Chengdu University of Traditional Chinese Medicine, No. 133 Jianshe Road, Lizhou District, Guangyuan City, Guangyuan 628000, Sichuan Province, China. qinchaonannong@163.com
Key Words	Pancreatitis; Inflammation; Chemokines; Protection; Aggravation
Core Tip	This study highlights the pivotal roles of chemokines in the pathogenesis of various types of pancreatitis, including acute, chronic, autoimmune, and pancreatic cancer. Chemokines like CCL2/MCP-1 and CXCL2 exacerbate acute pancreatitis by promoting neutrophil infiltration, whereas CXCL10 and CXCR3 contribute to chronic inflammation and fibrosis. CCL1–CCR8 interaction is critical for lymphocytic recruitment in autoimmune pancreatitis. Understanding the specific functions of these chemokines may lead to the development of novel therapeutic strategies targeting these inflammatory mediators.
Citation	Ni WF, Qin CC. Roles of chemokines in pancreatitis: A review. World J Gastrointest Pathophysiol 2025; In press

Received	2025-07-03 14:22
Peer-Review Started	2025-07-04 00:18
To Make the First Decision
Return for Revision	2025-08-15 01:00
Revised	2025-09-01 01:02
Second Decision	2025-10-20 02:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-21 02:51
Articles in Press	2025-10-21 02:51
Publication Fee Transferred	2025-09-05 08:43
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Typeset the Manuscript

ISSN	2150-5330 (online)
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