Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	111615
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation
Manuscript Source	Invited Manuscript
All Author List	Shivam Kalra, Manjeet Kumar Goyal, Kartikay Goyal, Rajdeep Singh, Ashita Rukmini Vuthaluru and Omesh Goyal
Funding Agency and Grant Number
Corresponding Author	Omesh Goyal, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. dromeshgoyal@gmail.com
Key Words	Constipation; Gastrointestinal motility; Colonic transit time; Abdominal radiography; Diagnostic techniques; Digestive system; Ethnic groups; Health care disparities
Core Tip	Colonic transit time (CTT) assessment using radiopaque markers (ROM) is a cost-effective, underutilized tool for subtyping functional constipation and guiding therapy. This review highlighted the need for standardized ROM CTT protocols tailored to regional transit characteristics, especially in Asian populations. It underscored the importance of multicentric normative data, clinician awareness, and technological innovations like artificial intelligence-assisted marker analysis to elevate the ROM CTT study from a research tool to a routine diagnostic modality.
Citation	Kalra S, Goyal MK, Goyal K, Singh R, Vuthaluru AR, Goyal O. Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation. World J Gastrointest Pharmacol Ther 2026; In press

Received	2025-07-04 00:51
Peer-Review Started	2025-07-04 00:51
First Decision by Editorial Office Director	2025-08-25 07:44
Return for Revision	2025-08-25 07:44
Revised	2025-08-25 23:52
Publication Fee Transferred
Second Decision by Editor	2026-01-07 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-07 09:22
Articles in Press	2026-01-07 09:22
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
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