BPG is committed to discovery and dissemination of knowledge
Articles in Press
10/11/2025 5:25:03 AM | Browse: 148 | Download: 13
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Unveiling Yiyi Fuzi Baijiang powder: Microecological and network pharmacology approach to ulcerative colitis treatment
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Liang-Kun Zhang, Wen-Chao Gu and Jian Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Project at Central Government Level |
No. 2060302 |
| Key Project of Traditional Chinese Medicine Science and Technology in Shandong Province |
No. Z-2023015 |
| Clinical Medical Science and Technology Innovation Program of Jinan Science and Technology Bureau |
No. 202328043 |
|
| Corresponding Author |
Jian Chen, MD, PhD, Jinan Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Lixia District, Jinan 250355, Shandong Province, China. chenjian860103@163.com |
| Key Words |
Yiyi Fuzi Baijiang powder; Chinese medicine; Ulcerative colitis; Gut microbiota; Microbiome; Intestinal flora; Network pharmacology; Molecular docking; Mechanism |
| Core Tip |
The therapeutic application of Yiyi Fuzi Baijiang powder (YFB) for ulcerative colitis (UC) extends beyond merely altering the structure and abundance of gut microbiota. Instead, it aims to restore dynamic equilibrium by comprehensively modulating the intestinal microecological balance, thereby facilitating disease recovery. Furthermore, it is hypothesized that YFB powder may exert its effects on UC through potential mechanisms involving the NFKB1, RELA, and nuclear factor kappa B inhibitor alpha regulatory pathways, as well as the cancer and adipocytokine signaling pathways. |
| Citation |
Zhang LK, Gu WC, Chen J. Unveiling Yiyi Fuzi Baijiang powder: Microecological and network pharmacology approach to ulcerative colitis treatment. World J Gastroenterol 2025; In press |
 |
Received |
|
2025-07-14 12:05 |
|
Peer-Review Started |
|
2025-07-14 12:07 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-07-24 09:00 |
|
Revised |
|
2025-08-06 12:34 |
|
Second Decision |
|
2025-10-11 02:46 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-10-11 05:25 |
|
Articles in Press |
|
2025-10-11 05:25 |
|
Publication Fee Transferred |
|
2025-08-07 07:05 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
|
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
