Publication Name	World Journal of Hepatology
Manuscript ID	111722
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Application of modified Charlson comorbidity index for predicting outcomes following adult living donor liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Gowtham Rajan, Amal Francis Sam, Akila Rajakumar, Dinesh Jothimani and Mohamed Rela
Funding Agency and Grant Number
Corresponding Author	Akila Rajakumar, FRCA, Head, MD, Department of Liver Transplant Anaesthesia and Intensive Care, Institute of Liver Disease and Transplantation, Dr. Rela Institute, No. 7 CLC Works Road, Chennai 600044, Tamil Nadu, India. drakila.rajakumar@gmail.com
Key Words	Charlson comorbidity index; Post living donor liver transplantation outcomes; Composite outcome scores in living donor liver transplantation; Charlson comorbidity index vs model for end-stage liver disease; Modified Charlson comorbidity index in liver transplantation; Outcome prediction in living donor liver transplantation
Core Tip	With advances in surgical techniques and perioperative care, the outcomes of liver transplantation have improved significantly encouraging its use in more elderly patients and those with more comorbidities. In addition to severity of liver disease, understanding the impact of extra hepatic comorbidities on the outcomes will help ion prognostication and risk stratification with appropriate resource planning. Charlson comorbidity index has been validated as a good predictor of long-term survival in varied clinical populations. With limited studies regarding its use in liver transplant patients, we attempted to study its applicability in our cohort of living donor liver transplant patients.
Citation	Rajan G, Sam AF, Rajakumar A, Jothimani D, Rela M. Application of modified Charlson comorbidity index for predicting outcomes following adult living donor liver transplantation. World J Hepatol 2025; In press

Received	2025-07-08 05:35
Peer-Review Started	2025-07-08 05:35
To Make the First Decision
Return for Revision	2025-08-08 08:43
Revised	2025-08-29 09:45
Second Decision	2025-11-24 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-24 09:30
Articles in Press	2025-11-24 09:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com