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Publication Name World Journal of Cardiology
Manuscript ID 111954
Country India
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Metabolic-dysfunction associated steatotic liver disease and heart failure with preserved ejection fraction: A state-of-the-art review
Manuscript Source Invited Manuscript
All Author List Ajit Singh Brar, Tejasvini Khanna, Aalam Sohal, Juniali Hatwal, Vishal Sharma, Carol Singh, Akash Batta, Praveen Chandra and Bishav Mohan
Funding Agency and Grant Number
Corresponding Author Akash Batta, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Key Words Metabolic dysfunction-associated steatotic liver disease; Heart failure with preserved ejection fraction; Diabetes mellitus; Obesity; Hypertension; Dyslipidemia; Obstructive sleep apnea; Inflammation; Metabolic dysfunction
Core Tip The ever-changing terminology of metabolic dysfunction–associated steatotic liver disease (MASLD) to encompass metabolic dysfunction truly reflects its systemic impact beyond the liver. Cardiovascular diseases remain the leading cause of MASLD related morbidity and mortality. Amongst the various cardiovascular diseases linked to MASLD, heart failure with preserved ejection fraction (HFpEF) is most closely related to MASLD, sharing a pathophysiologic foundation with MASLD, and rooted in common metabolic risk factors. This review explores the intertwined mechanisms linking MASLD and HFpEF, highlighting their clinical convergence and therapeutic relevance.
Citation Brar AS, Khanna T, Sohal A, Hatwal J, Sharma V, Singh C, Batta A, Chandra P, Mohan B. Metabolic-dysfunction associated steatotic liver disease and heart failure with preserved ejection fraction: A state-of-the-art review. World J Cardiol 2025; In press
Received
2025-07-14 03:08
Peer-Review Started
2025-07-14 03:08
To Make the First Decision
Return for Revision
2025-07-17 10:15
Revised
2025-08-04 18:06
Second Decision
2025-11-24 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-11-24 07:18
Articles in Press
2025-11-24 07:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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