Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	112019
Country	Singapore

Category	Critical Care Medicine
Manuscript Type	Review
Article Title	Constipation in critically ill adults
Manuscript Source	Invited Manuscript
All Author List	Yuri Kim and Kay C See
Funding Agency and Grant Number
Corresponding Author	Yuri Kim, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore. yurikim6232@gmail.com
Key Words	Constipation; Gastrointestinal motility; Bowel dysfunction; Critical illness; Intensive care unit
Core Tip	Constipation is a frequently overlooked complication in critically ill adults that adversely affects clinical outcomes. This review synthesizes current evidence on its complex pathophysiology, multifactorial etiology and diagnostic challenges within the intensive care unit. It underscores the importance of timely recognition and comprehensive management strategies combining both therapeutic and preventive strategies. By highlighting gaps in standardized diagnostic criteria and therapeutic protocols, this article advocates for further research to establish evidence-based guidelines aimed at improving patient prognosis and quality of care in the intensive care unit.
Citation	Kim Y, See KC. Constipation in critically ill adults. World J Gastrointest Pathophysiol 2025; In press

Received	2025-07-16 01:39
Peer-Review Started	2025-07-16 01:39
First Decision by Editorial Office Director	2025-08-14 06:01
Return for Revision	2025-08-14 06:01
Revised	2025-08-25 15:03
Publication Fee Transferred
Second Decision by Editor	2025-12-01 02:57
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-01 10:39
Articles in Press	2025-12-01 10:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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