Publication Name	World Journal of Psychiatry
Manuscript ID	112022
Country	Malaysia

Category	Psychology, Multidisciplinary
Manuscript Type	Systematic Reviews
Article Title	Forever chemicals and mental health: A systematic review of per- and polyfluoroalkyl substances-related psychiatric outcomes and mechanistic insights
Manuscript Source	Invited Manuscript
All Author List	Yi-Lin Jiang, Narina A Samah and Zhan-Shuo Xiao
Funding Agency and Grant Number
Corresponding Author	Yi-Lin Jiang, PhD, Faculty of Educational Sciences and Technology, Universiti Teknologi Malaysia, Skudai, Johor Bahru 81310, Johor, Malaysia. yilinjiangs@foxmail.com
Key Words	Per- and polyfluoroalkyl substances; Mental health; Psychiatric outcomes; Depression and anxiety; Environmental exposure; Vulnerable populations; Neurodevelopmental disorders
Core Tip	This article synthesizes recent evidence linking per- and polyfluoroalkyl substances (PFAS) exposure to psychiatric disorders. It highlights the growing relevance of PFAS in psychiatric research, especially concerning children, pregnant women, and socioeconomically vulnerable populations. By examining epidemiological trends and biological mechanisms, the review underscores the urgent need for interdisciplinary research and policy action to mitigate the mental health risks posed by these persistent environmental contaminants.
Citation	Jiang YL, Samah NA, Xiao ZS. Forever chemicals and mental health: A systematic review of per- and polyfluoroalkyl substances-related psychiatric outcomes and mechanistic insights. World J Psychiatry 2025; In press

Received	2025-07-16 01:53
Peer-Review Started	2025-07-16 01:54
To Make the First Decision
Return for Revision	2025-07-24 07:57
Revised	2025-07-27 03:40
Second Decision	2025-11-05 09:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-12 09:52
Articles in Press	2025-11-12 09:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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