Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	112169
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Serum inflammatory biomarkers can predict clinical outcomes in patients with sepsis-associated gastrointestinal dysfunction
Manuscript Source	Unsolicited Manuscript
All Author List	You-Hui Liu, Qing-Yang Chen, Fei-Yue Dai and Xin-Yu Chen
Funding Agency and Grant Number	Funding Agency Grant Number National Chinese Medicine Advantage Specialty Construction Project Czxm-zzyxk-2024001
Corresponding Author	Xin-Yu Chen, MD, Department of Internal Medicine, The First Hospital of Hunan University of Chinese Medicine, No. 95 Shaoshan Middle Road, Yuhua District, Changsha 410007, Hunan Province, China. chenxinyuchen1@163.com
Key Words	Serum inflammatory biomarkers; Procalcitonin; C-reactive protein; Interleukin-6/10; Sepsis; Gastrointestinal dysfunction; Clinical outcome; Predictive value
Core Tip	This study analyzed 117 patients with sepsis-associated gastrointestinal dysfunction and identified procalcitonin, C-reactive protein, tumor necrosis factor-alpha, and interleukin-6/10 as key biomarkers of disease severity and prognosis. Elevated C-reactive protein and tumor necrosis factor-alpha levels and higher Sequential Organ Failure Assessment scores increased the likelihood of poor outcomes, while combining multiple biomarkers significantly improved predictive accuracy.
Citation	Liu YH, Chen QY, Dai FY, Chen XY. Serum inflammatory biomarkers can predict clinical outcomes in patients with sepsis-associated gastrointestinal dysfunction. World J Gastrointest Surg 2025; In press

Received	2025-09-09 09:15
Peer-Review Started	2025-09-09 09:15
First Decision by Editorial Office Director	2025-09-30 07:49
Return for Revision	2025-09-30 07:49
Revised	2025-10-30 13:33
Publication Fee Transferred	2025-11-03 14:01
Second Decision by Editor	2025-12-15 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-16 02:33
Articles in Press	2025-12-16 02:33
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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