Publication Name	World Journal of Diabetes
Manuscript ID	112171
Country	Taiwan

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Cohort Study
Article Title	Real-world evidence for herbal medicine benefit in 9728 type 2 diabetes patients-peridonotitis risk and ambulatory care utilization
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Wei Lin, Chieh-Tsung Yen, Hanoch Livneh, Hua-Lung Huang, Ming-Chi Lu, Wei-Jen Chen and Tzung-Yi Tsai
Funding Agency and Grant Number
Corresponding Author	Tzung-Yi Tsai, Assistant Professor, Consultant, PhD, Researcher, Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2 Minsheng Road, Chiayi 62247, Taiwan. dm732024@tzuchi.com.tw
Key Words	Type 2 diabetes; Periodontitis; Medicinal herbs; Cohort study; Interdisciplinary collaboration; Risk
Core Tip	As periodontitis is a common and frequently occurring condition following type 2 diabetes (T2D) onset and insidiously triples cardiorenal mortality in individuals with diabetes, we conducted a population-based cohort study to gain deeper insight into the relationship between medicinal herb use and incident periodontitis. In this study, adding medicinal herbs to routine care for more than 2 years benefited T2D individuals by lowering periodontitis risk as much as 52%; moreover, this approach substantially reduced the subsequent use of periodontitis-related ambulatory services, underscoring the increasing importance of interdisciplinary healthcare.
Citation	Lin WW, Yen CT, Livneh H, Huang HL, Lu MC, Chen WJ, Tsai TY. Real-world evidence for herbal medicine benefit in 9728 type 2 diabetes patients-peridonotitis risk and ambulatory care utilization. World J Diabetes 2025; In press

Received	2025-07-21 08:37
Peer-Review Started	2025-07-22 00:07
To Make the First Decision
Return for Revision	2025-08-27 07:52
Revised	2025-09-10 03:35
Second Decision	2025-10-20 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-20 09:52
Articles in Press	2025-10-20 09:52
Publication Fee Transferred	2025-09-16 00:57
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com