Publication Name	World Journal of Clinical Oncology
Manuscript ID	112369
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Obesity and colorectal cancer risk: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Lachlan James Chun-Lok Leung, Rohan Sharad Sharma, Brandon Cheng, HM Kasuni Akalanka and Vinod Gopalan
Funding Agency and Grant Number
Corresponding Author	Lachlan James Chun-Lok Leung, School of Medicine and Dentistry, Griffith University, 20f Parklands Dr, Southport, Gold Coast 4215, Queensland, Australia. leunglachlan@gmail.com
Key Words	Body mass index; Colorectal cancer; Meta-analysis; Obesity; Systematic review
Core Tip	This systematic review and meta-analysis identify obesity as a modifiable risk factor for colorectal cancer (CRC) in both men and women. The risk is further heightened by associated lifestyle factors such as poor diet, physical inactivity, and the presence of comorbidities, including diabetes. These elements contribute synergistically to the development of CRC, highlighting the importance of recognising obesity not just as a health concern but as a cancer-promoting condition. Implementing earlier and targeted screening strategies for CRC in obese individuals can play a key role in reducing incidence and improving outcomes through earlier detection and intervention.
Citation	Leung LJCL, Sharma RS, Cheng B, Akalanka HMK, Gopalan V. Obesity and colorectal cancer risk: A systematic review and meta-analysis. World J Clin Oncol 2025; In press

Received	2025-07-25 01:01
Peer-Review Started	2025-07-25 01:01
To Make the First Decision
Return for Revision	2025-08-06 10:20
Revised	2025-08-13 03:18
Second Decision	2025-11-27 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-27 11:17
Articles in Press	2025-11-27 11:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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