Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	112485
Country	Kuwait

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Feasibility and safety of endoscopic ultrasound-guided liver biopsy to diagnose parenchymal liver disease: A multi-centre retrospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Ali A Alali, Nargess Ali, Ahmad Hashim, Dalal Alhaqqan, Wadha Aljasser, Abdulaziz Almudaires, Shahad Bastaki, Ahmad Alhashmi and Ahmad Altaleb
Funding Agency and Grant Number
Corresponding Author	Ali A Alali, Assistant Professor, Department of Medicine, Faculty of Medicine, Kuwait University, Block 4, Jaberya 13110, Kuwait. alali.a@ku.edu.kw
Key Words	Endoscopic ultrasound; Liver biopsy; Parenchymal liver disease; Fine needle aspiration; Fine needle biopsy
Core Tip	Endoscopic ultrasound-guided liver biopsy (EUS-LB) has recently been introduced as an endoscopic method for obtaining liver biopsy in patients with suspected parenchymal liver disease. However, the efficacy and safety of this approach remain unclear. Furthermore, some uncertainty exists in the most appropriate needle size and suction technique to achieve an optimal histological specimen. This multicenter retrospective study found a high diagnostic yield for EUS-LB with a low rate of serious adverse events. In addition, the use of a 19-gauge fine needle biopsy needle, the wet-heparin suction technique, and performing ≤ 2 passes was associated with improved quality of the specimen obtained without increasing the risk of adverse events.
Citation	Alali AA, Ali N, Hashim A, Alhaqqan D, Aljasser W, Almudaires A, Bastaki S, Alhashmi A, Altaleb A. Feasibility and safety of endoscopic ultrasound-guided liver biopsy to diagnose parenchymal liver disease: A multi-centre retrospective cohort study. World J Gastrointest Endosc 2025; In press

Received	2025-07-29 03:43
Peer-Review Started	2025-07-29 03:43
To Make the First Decision
Return for Revision	2025-08-27 15:13
Revised	2025-09-08 15:13
Second Decision	2025-10-21 03:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-21 08:10
Articles in Press	2025-10-21 08:10
Publication Fee Transferred	2025-09-09 17:33
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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