Publication Name	World Journal of Gastroenterology
Manuscript ID	112518
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Diagnostic accuracy of stereomicroscopy assessment of invasion depth in ex vivo specimens of early gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Jing Wang, Lin Chang, Dong-Feng Niu, Yan Yan, Chang-Qi Cao, Shi-Jie Li and Qi Wu
Funding Agency and Grant Number	Funding Agency Grant Number Hygiene and Health Development Scientific Research Fostering Plan of Haidian District Beijing HP2024-19-503002 Beijing Municipal Administration of Hospitals Incubating Program PX2024041
Corresponding Author	Qi Wu, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Endoscopy Center, Peking University Cancer Hospital and Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. wuqi1973@bjmu.edu.cn
Key Words	Diagnostic accuracy; Early gastric cancer; Endoscopic submucosal dissection; Invasion depth; Stereomicroscopy
Core Tip	This study demonstrates that stereomicroscopy effectively assesses invasion depth in early gastric cancer, achieving 93.5% accuracy for non-ulcerated lesions, although the overall accuracy was 74.0% and only 35.8% for ulcerated lesions. Tumor size (21-30 mm) and ulceration are key misdiagnosis risk factors. These findings could guide stratified endoscopic submucosal dissection strategy.
Citation	Wang J, Chang L, Niu DF, Yan Y, Cao CQ, Li SJ, Wu Q. Diagnostic accuracy of stereomicroscopy assessment of invasion depth in ex vivo specimens of early gastric cancer. World J Gastroenterol 2025; In press

Received	2025-08-06 14:58
Peer-Review Started	2025-08-06 14:58
To Make the First Decision
Return for Revision	2025-09-25 09:10
Revised	2025-10-08 14:20
Second Decision	2025-11-04 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-04 09:00
Articles in Press	2025-11-04 09:00
Publication Fee Transferred	2025-10-20 13:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com