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Publication Name World Journal of Diabetes
Manuscript ID 112580
Country China
Category Endocrinology & Metabolism
Manuscript Type Minireviews
Article Title Electroacupuncture in glycemic control: Transitioning from clinical controversies to potential basic research  
Manuscript Source Invited Manuscript
All Author List Shuai-Yan Wang, Chen-Xi Deng, Yi-Ning Huang, Mei-Xin Tian, Si-Yu Zhuang, Yi-Fan Deng, Bin Xu and Tian-Cheng Xu
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (Youth Science Fund Project) 82305376
Jiangsu Provincial Science and Technology Think Tank Program (Youth) in 2025 JSKX0125035
Jiangsu Provincial Youth Science and Technology Talent Support Program in 2024 JSTJ-2024-380
China Association of Acupuncture-Moxibustion Youth Talent Support Program 2024-2026ZGZJXH-QNRC005
National Undergraduate Innovation Training Program 202410315020Z
Provincial Undergraduate Innovation Training Program 202410315149Y
Corresponding Author Bin Xu, Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, No. 138 Xianlin Road, Nanjing 210023, Jiangsu Province, China. xubin@njucm.edu.cn
Key Words Electroacupuncture; Blood glucose management; Clinical controversies; Basic research in acupuncture; Auricular acupuncture; Body acupuncture
Core Tip This review examines electroacupuncture (EA) for glycemic control, addressing clinical controversies and underlying mechanisms. While EA shows promise in reducing blood glucose levels in type 2 diabetes, current clinical trials are limited by small sample sizes and heterogeneous designs, lacking robust international consensus. Basic research indicates that EA’s hypoglycemic effects involve modulating the neuro-endocrine-immune axis, enhancing insulin signaling, and improving gut microbiota. Future work should focus on optimizing EA protocols and developing standardized interventions to advance its clinical application in diabetes management.  
Citation Wang SY, Deng CX, Huang YN, Tian MX, Zhuang SY, Deng YF, Xu B, Xu TC. Electroacupuncture in glycemic control: Transitioning from clinical controversies to potential basic research. World J Diabetes 2025; In press
Received
2025-07-31 01:59
Peer-Review Started
2025-07-31 06:49
To Make the First Decision
Return for Revision
2025-08-28 09:18
Revised
2025-09-05 02:12
Second Decision
2025-10-11 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-11-06 10:09
Articles in Press
2025-11-06 10:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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