Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	112588
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Liver clock: Malalignment and entrainment therapeutics
Manuscript Source	Invited Manuscript
All Author List	Shaiphali Sharma, Shreya Pandey and Ajay Kumar Mishra
Funding Agency and Grant Number
Corresponding Author	Ajay Kumar Mishra, Assistant Professor, Department of Hepatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raibareilly Road,, Lucknow 226014, Uttar Pradesh, India. ajaymishrapandit@gmail.com
Key Words	Circadian rhythm; Liver clock; Metabolic dysfunction-associated steatotic liver disease; Suprachiasmatic nucleus; Clock gene; Melatonin; Life style disorders
Core Tip	Liver clock is peripheral clock of hepatocytes concerned with metabolic genes and functions. It is desynchronised to central clock in metabolic and life style disorders. It can be resynchronised by various life style and therapeutic measures including modifying eating behaviours, light exposure, excercise or activity modification. This mini-review discusses causes of misalignment of liver clock and how to fix them.
Citation	Sharma S, Pandey S, Mishra AK. Liver clock: Malalignment and entrainment therapeutics. World J Gastrointest Pharmacol Ther 2025; In press

Received	2025-08-04 06:34
Peer-Review Started	2025-08-04 06:34
First Decision by Editorial Office Director	2025-08-28 09:28
Return for Revision	2025-08-28 09:28
Revised	2025-09-26 13:27
Publication Fee Transferred
Second Decision by Editor	2025-12-12 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-12 07:39
Articles in Press	2025-12-12 07:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
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