Publication Name	World Journal of Virology
Manuscript ID	112590
Country	Pakistan

Category	Virology
Manuscript Type	Review
Article Title	Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies
Manuscript Source	Invited Manuscript
All Author List	Ammara Abdul Majeed, Maham Sarfraz and Amna Subhan Butt
Funding Agency and Grant Number
Corresponding Author	Amna Subhan Butt, Associate Professor, Department of Medicine, Aga Khan University Hospital, Stadium Road, Karachi 74800, Pakistan. amna.subhan@aku.edu
Key Words	Disease outbreak; Emerging infectious disease; Hepatitis A vaccine; Fulminant hepatic failure; Endemic diseases
Core Tip	The epidemiology of hepatitis A is undergoing a profound shift, driven by changing socioeconomic conditions, living standards worldwide and ongoing viral evolution. This has resulted in a shift in epidemiology, with decreasing exposure to the virus among children, leaving adolescent and adult populations susceptible to more clinically significant disease. This change leads to more severe disease in older populations, highlighting the need for updated vaccination guidelines targeting susceptible adults, vigilant surveillance to monitor viral evolution and antigenic variation, and strengthened public health measures including enhanced hygiene and outbreak prevention strategies.
Citation	Majeed AA, Sarfraz M, Butt AS. Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies. World J Virol 2025; In press

Received	2025-07-31 02:10
Peer-Review Started	2025-07-31 02:10
First Decision by Editorial Office Director	2025-10-11 05:46
Return for Revision	2025-10-11 05:46
Revised	2025-10-25 11:48
Publication Fee Transferred
Second Decision by Editor	2025-12-16 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-16 10:53
Articles in Press	2025-12-16 10:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3249 (online)
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