Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	112729
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Risk factors for esophageal pain after peroral endoscopic myotomy under general anesthesia: A retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Wei Yin, Wen-Qi Zhang, Han Xu, Ting-Ting Wen and Sheng-Wen Song
Funding Agency and Grant Number	Funding Agency Grant Number the Special Research Project on Optimal Management of Acute Pain, Wu Jie-ping Medical Foundation 320.6750.2024-15.101
Corresponding Author	Sheng-Wen Song, MD, Department of Anesthesiology, the First Affiliated Hospital, Zhejiang University School of Medicine, Wenyi West Road 1367, Hangzhou City, Zhejiang Province, China, Hangzhou 310000, Zhejiang Province, China. songsheng_wen@126.com
Key Words	Achalasia; Eckardt score; Numerical rating scale; Peroral endoscopic myotomy; Post-peroral endoscopic myotomy pain; Preoperative anxiety
Core Tip	This study revealed that the incidence of postoperative pain in patients with achalasia who underwent peroral endoscopic esophageal myotomy (POEM) significantly increased, with 26.8% of patients experiencing at least moderate-intensity pain (numerical rating scale score ≥ 4). Furthermore, preoperative anxiety and a high Eckardt score were independent risk factors for post-POEM pain. These findings suggest that incorporating clinical symptom assessment, psychological status screening, and optimized analgesic strategies into preoperative anesthesia management is crucial for preventing and relieving postoperative pain.
Citation	Yin JW, Zhang WQ, Xu H, Wen TT, Song SW. Risk factors for esophageal pain after peroral endoscopic myotomy under general anesthesia: A retrospective study. World J Gastrointest Surg 2025; In press

Received	2025-08-05 03:43
Peer-Review Started	2025-08-05 03:44
To Make the First Decision
Return for Revision	2025-08-27 10:58
Revised	2025-09-06 15:40
Second Decision	2025-10-11 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-11 06:14
Articles in Press	2025-10-11 06:14
Publication Fee Transferred	2025-09-10 01:56
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Typeset the Manuscript

ISSN	1948-9366 (online)
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