Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	112759
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Cryoballoon treatment of endoscopically unresectable duodenal adenomas
Manuscript Source	Unsolicited Manuscript
All Author List	Negar Modirian, Mike T Wei and Shai Friedland
Funding Agency and Grant Number
Corresponding Author	Mike T Wei, Department of Gastroenterology and Hepatology, Stanford University Medical Center, 300 Pasteur Drive, Palo Alto, CA 94305, United States. mtwei@stanford.edu
Key Words	Cryoballoon; Cryotherapy; Duodenal adenomas; Endoscopic mucosal resection; Endoscopic submucosal dissection
Core Tip	Conventional procedures for treating fibrotic, recurring, or widespread duodenal adenomas, such as snare polypectomy and endoscopic mucosal resection, may have limitations. This multicenter retrospective study examines cryoballoon ablation as a novel treatment for such complex lesions. The findings suggest that cryoballoon therapy is a safe and potentially successful treatment for non-circumferential flat adenomas, particularly those complicated by past resections and fibrosis. However, its effectiveness may be restricted in large circumferential lesions.
Citation	Modirian N, Wei MT, Friedland S. Cryoballoon treatment of endoscopically unresectable duodenal adenomas. World J Gastrointest Endosc 2025; In press

Received	2025-08-06 16:14
Peer-Review Started	2025-08-06 16:14
To Make the First Decision
Return for Revision	2025-09-17 17:51
Revised	2025-10-22 23:25
Second Decision	2025-11-17 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-17 03:29
Articles in Press	2025-11-17 03:29
Publication Fee Transferred	2025-10-28 17:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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