Publication Name	World Journal of Meta-Analysis
Manuscript ID	112793
Country	Pakistan

Category	Anesthesiology
Manuscript Type	Meta-Analysis
Article Title	Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Amna Hassni, Abdul Hannan Siddiqui, Mahdeem Shahid, Abia Shariq, Huma Anwar, Khizra Nadeem, Alina Anjum, Hamida Memon, Ameer Talha, Sarosh Khan, Yusra Faisal, Maheen Naveed, Abdul Moeed and Salim Surani
Funding Agency and Grant Number
Corresponding Author	Abdul Hannan Siddiqui, Researcher, Department of Internal Medicine, Dow University of Health Sciences, Mission Road, Karachi 74200, Sindh, Pakistan. abdul.siddiqui19@dmc.duhs.edu.pk
Key Words	Analgesia; Dexmedetomidine; Flexible bronchoscopy; Midazolam; Propofol; Sedation; Meta-analysis
Core Tip	This meta-analysis assessed the effectiveness of dexmedetomidine (DEX), a selective alpha-2 adrenergic receptor agonist, as a sedative agent in flexible bronchoscopy. Compared with other sedative and analgesic regimens, DEX notably reduced the risk of hypoxemia and tachycardia, while mildly improving patient and physician satisfaction. Although extra sedation was administered where necessary, the overall safety profiles were favorable. These findings suggest that DEX is a promising option for patients with compromised respiratory capacity, providing enhanced safety and tolerability during bronchoscopy.
Citation	Hassni A, Siddiqui AH, Shahid M, Shariq A, Anwar H, Nadeem K, Anjum A, Memon H, Talha A, Khan S, Faisal Y, Naveed M, Moeed A, Surani S. Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis. World J Meta-Anal 2025; In press

Received	2025-08-06 15:35
Peer-Review Started	2025-08-06 15:35
First Decision by Editorial Office Director	2025-09-02 10:27
Return for Revision	2025-09-02 10:27
Revised	2025-09-26 10:44
Publication Fee Transferred
Second Decision by Editor	2025-12-26 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-26 07:18
Articles in Press	2025-12-26 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2308-3840 (online)
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