Publication Name	World Journal of Nephrology
Manuscript ID	112796
Country	Saudi Arabia

Category	Urology & Nephrology
Manuscript Type	Systematic Reviews
Article Title	Acute kidney injury induced by topical hair straightening products: A systematic review
Manuscript Source	Unsolicited Manuscript
All Author List	Ahmad B Aamir, Rabia Latif, FNU Sorath, Subhash Chander, Aamna Latif, Zubair Rahaman, Yaqub N Mohammed, Om Parkash, Poonam Devi, Ghala A Hassan and Batool M Alalwan
Funding Agency and Grant Number
Corresponding Author	Rabia Latif, PhD, Professor, Department of Physiology, Imam Abdulrahman Bin Faisal University, King Faisal Road, DAMMAM 31441, Saudi Arabia. rlhussain@iau.edu.sa
Key Words	Acute kidney injury; Formaldehyde; Glyoxylic acid; Hair; Nephropathy; Renal; Toxicity
Core Tip	This systematic review is the first comprehensive synthesis of reported cases linking topical hair-straightening products to acute kidney injury (AKI). Analyzing 36 incidents of AKI in 34 female patients, the current study highlights that topical application of hair straightening chemicals can trigger AKI through mechanisms involving calcium oxalate nephropathy and/or interstitial nephritis. Most patients recovered with conservative or steroid-based therapy. The study underscores the need for clinician awareness and regulatory scrutiny, revealing that hair straightening products may not be as safe as presumed.
Citation	Aamir AB, Latif R, Sorath F, Chander S, Latif A, Rahaman Z, Mohammed YN, Parkash O, Devi P, Hassan GA, Alalwan BM. Acute kidney injury induced by topical hair straightening products: A systematic review. World J Nephrol 2025; In press

Received	2025-08-11 14:22
Peer-Review Started	2025-08-11 14:22
First Decision by Editorial Office Director	2025-10-22 08:53
Return for Revision	2025-10-22 08:53
Revised	2025-10-29 09:11
Publication Fee Transferred	2025-10-30 18:04
Second Decision by Editor	2025-12-11 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-11 08:56
Articles in Press	2025-12-11 08:56
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ISSN	2220-6124 (online)
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