Publication Name	World Journal of Diabetes
Manuscript ID	112885
Country	China

Category	Toxicology
Manuscript Type	Basic Study
Article Title	Gut microbiota's role in lead-induced neural damage in diabetic mice
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Jia Ding, Chao-Qun Liu, Xin-Yi Tang, Zhi-Bin Shang, Xu Liang, Tao Tao, Ru-Xi Liu, Qiong-Yun Jiang, Yan-Fang Qiu and Yi Sun
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82060586 Natural Science Foundation of Guangdong Province 2023GXNSFAA026122 China Scholarship Council 202208455012 National Guangxi College Students Innovation and Entrepreneurship Training Program S202410601154，X202310601246，X202310601245
Corresponding Author	Yi Sun, Department of Toxicology, Guilin Medical University, No. 1 Zhiyuan Road, Lingui District, Guilin 541000, Guangxi Zhuang Autonomous Region, China. sunyide163@163.com
Key Words	Diabetes; Lead exposure; Proteomics; Gut microbiota; Neurotoxicity
Core Tip	This study identified the additive effects of concurrent lead exposure and diabetes on neurotoxicity and provided a preliminary exploration of the mechanisms by which gut microbiota regulated the brain differential protein expression and ultimately affected neurological function, based on proteomics and gut microbiota analysis.
Citation	Ding WJ, Liu CQ, Tang XY, Shang ZB, Liang X, Tao T, Liu RX, Jiang QY, Qiu YF, Sun Y. Gut microbiota's role in lead-induced neural damage in diabetic mice. World J Diabetes 2025; In press

Received	2025-08-13 01:01
Peer-Review Started	2025-08-13 06:47
To Make the First Decision
Return for Revision	2025-09-09 09:34
Revised	2025-09-19 07:36
Second Decision	2025-11-13 02:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-28 08:46
Articles in Press	2025-11-28 08:46
Publication Fee Transferred	2025-09-24 02:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com