Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	112896
Country	China

Category	Oncology
Manuscript Type	Minireviews
Article Title	Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Yu-Zhou Zhang, Yuan-Ze Tang, Yun-Xuan He, Shu-Tong Pan, Hao-Cheng Dai, Yu Liu and Hai-Feng Zhou
Funding Agency and Grant Number
Corresponding Author	Hai-Feng Zhou, MD, PhD, Department of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. hfzhou_ir@sina.com
Key Words	Hepatocellular carcinoma; Immune status; Phenotype; Multimodal parameters; Prognosis
Core Tip	The immune status of hepatocellular carcinoma patients can be comprehensively assessed using multimodal phenomics analyses, which include clinical features to provide general patient information, routine blood tests to evaluate metabolism and function, immune cell subsets to analyze immune system composition, imaging to visualize tumor morphology and anatomical relationships, and immunohistochemical markers to detect antigens in tumor tissue. By integrating these parameters through multimodal phenomics analyses, we aim to enhance the evaluation of prognosis and clinical outcomes for hepatocellular carcinoma patients.
Citation	Zhang YZ, Tang YZ, He YX, Pan ST, Dai HC, Liu Y, Zhou HF. Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press

Received	2025-08-13 07:41
Peer-Review Started	2025-08-13 07:42
To Make the First Decision
Return for Revision	2025-10-13 11:25
Revised	2025-10-27 10:38
Second Decision	2025-11-28 03:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-28 09:08
Articles in Press	2025-11-28 09:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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