Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	112943
Country	Israel

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Low-volume bowel preparation provides safe and effective pan-enteric capsule endoscopy in suspected or established Crohn’s disease
Manuscript Source	Unsolicited Manuscript
All Author List	Snir Livne, Nathaniel Aviv Cohen, Naomi Fliss-Isakov, Moshe Leshno, Nitsan Maharshak, Eva Niv and Liat Deutsch
Funding Agency and Grant Number
Corresponding Author	Liat Deutsch, MD, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, 6 Weizmann St., Tel Aviv 6423906, Israel. liatml@tlvmc.gov.il
Key Words	Pan-enteric capsule endoscopy; Bowel preparation; Crohn’s disease; Low-volume protocol; Completion rate
Core Tip	This study evaluates a novel low-volume, sulfate-free bowel preparation (LVP) protocol for pan-enteric capsule endoscopy compared to the standard high-volume protocol. Despite the substantially lower volume, LVP achieved comparable completion rates and adequate colonic cleansing. A pooled analysis across cohorts supports these findings and suggests improved colonic visualization with LVP over high-volume protocol. LVP may therefore represent a safe, effective, and potentially more patient-friendly alternative for pan-enteric capsule endoscopy preparation, particularly in the evaluation of Crohn’s disease.
Citation	Livne S, Cohen NA, Fliss-Isakov N, Leshno M, Maharshak N, Niv E, Deutsch L. Low-volume bowel preparation provides safe and effective pan-enteric capsule endoscopy in suspected or established Crohn’s disease. World J Gastrointest Endosc 2025; In press

Received	2025-08-11 15:02
Peer-Review Started	2025-08-11 15:02
First Decision by Editorial Office Director	2025-09-23 09:47
Return for Revision	2025-09-24 21:14
Revised	2025-10-07 16:50
Publication Fee Transferred
Second Decision by Editor	2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-02 02:43
Articles in Press	2025-12-02 02:43
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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