Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	112988
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Comparison of epidural anesthesia and intravenous self-control analgesia on postoperative recovery quality in duodenectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Pan-Pan Li, Qiang Qu and Chang-Hui Shao
Funding Agency and Grant Number
Corresponding Author	Chang-Hui Shao, Department of Anesthesiology, Chengdu Integrated TCM and Western Medicine Hospital, No. 18 Wanxiang North Road, Shiyang Street, Wuhou District, Chengdu 610000, Sichuan Province, China. shao_hui1986@163.com
Key Words	Epidural anesthesia; Intravenous patient-controlled analgesia; Pancreaticoduodenectomy; Postoperative recovery; Pain management; Pulmonary complications; Bowel function; Enhanced recovery after surgery; Stress response; Patient satisfaction
Core Tip	This retrospective study compared epidural anesthesia (EA) with intravenous patient-controlled analgesia in patients undergoing pancreaticoduodenectomy. Using propensity score matching, the study found that EA significantly improved postoperative outcomes, including pain control, bowel function recovery, pulmonary complications, and patient satisfaction. EA was also associated with reduced inflammatory response and enhanced respiratory function. Subgroup analysis revealed greater benefits of EA in elderly patients and those with comorbidities. These findings support the use of EA as a key component of enhanced recovery protocols for major abdominal surgery.
Citation	Li PP, Qu Q, Shao CH. Comparison of epidural anesthesia and intravenous self-control analgesia on postoperative recovery quality in duodenectomy. World J Gastrointest Surg 2025; In press

Received	2025-08-26 09:20
Peer-Review Started	2025-08-26 09:20
To Make the First Decision
Return for Revision	2025-09-16 07:25
Revised	2025-09-28 14:06
Second Decision	2025-11-17 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-17 03:47
Articles in Press	2025-11-17 03:47
Publication Fee Transferred	2025-10-10 08:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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