Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	113046
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Short-term outcomes of laparoscopic-assisted transanal vs laparoscopic total mesorectal excision for mid-to-low rectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Qi Huang, Yue Li, Shi-Dong Feng, Yu-Chen Fang, Yuan-Hang Zhou, Da-Wei Li and Zhi-Wei Liao
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Baoshan District Science and Technology Commission Special Fund for Scientific and Technological Innovation Projects No. 19-E-37
Corresponding Author	Zhi-Wei Liao, MD, Department of General Surgery, RenHe Hospital, BaoShan District, No. 1999 Changjiang West Road, Shanghai 200431, China. rhyylzw@163.com
Key Words	Rectal cancer; Laparoscopic-assisted transanal total mesorectal excision; Laparoscopic total mesorectal excision; Low rectal cancer; Oncological outcomes; Postoperative recovery
Core Tip	This retrospective study compared laparoscopic-assisted transanal total mesorectal excision (TaTME) with traditional laparoscopic total mesorectal excision in 138 patients with mid-to-low rectal cancer. TaTME demonstrated significant advantages including reduced intraoperative blood loss, superior oncological outcomes with lower circumferential resection margin positivity rates and higher lymph node harvest, accelerated postoperative recovery, attenuated inflammatory response, and better anal function preservation. Multivariate analysis identified TaTME as an independent protective factor for good anal function. These findings suggest TaTME is a safer and more effective surgical approach for mid-to-low rectal cancer, warranting broader clinical adoption.
Citation	Huang Q, Li Y, Feng SD, Fang YC, Zhou YH, Li DW, Liao ZW. Short-term outcomes of laparoscopic-assisted transanal vs laparoscopic total mesorectal excision for mid-to-low rectal cancer. World J Gastrointest Surg 2025; In press

Received	2025-09-03 09:02
Peer-Review Started	2025-09-03 09:02
To Make the First Decision
Return for Revision	2025-09-25 03:15
Revised	2025-10-09 14:56
Second Decision	2025-11-19 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-19 08:07
Articles in Press	2025-11-19 08:07
Publication Fee Transferred	2025-10-15 01:45
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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