Publication Name	World Journal of Transplantation
Manuscript ID	113075
Country	United Kingdom

Category	Transplantation
Manuscript Type	Retrospective Cohort Study
Article Title	Robot-assisted vs hand-assisted laparoscopic donor nephrectomy in the United Kingdom: Equivalent outcomes in the first national series
Manuscript Source	Invited Manuscript
All Author List	Chrysanthos D Christou, Savvas Antoniadis, Avishek Majumder, Rhana Zakri, Jonathon Olsburgh, Chris Callaghan, Georgios Papadakis, Kiran Sran, Martin Drage, Karel Decaestecker, Ben Challacombe, Nicos Kessaris and Ioannis Loukopoulos
Funding Agency and Grant Number
Corresponding Author	Ioannis Loukopoulos, Consultant, Department of Renal Transplantation, Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London SE1 9RT, United Kingdom. i.loukopoulos@nhs.net
Key Words	Robot-assisted donor nephrectomy; Hand-assisted donor nephrectomy; Living kidney donation; Surgical outcomes; Learning curve; Minimally invasive surgery; United Kingdom experience
Core Tip	This is the first United Kingdom study to compare robot-assisted (RALDN) and hand-assisted laparoscopic donor nephrectomy outcomes. In a matched cohort of 140 donors, both techniques achieved equivalent safety and efficacy, with no differences in donor or recipient renal function at one year. Although RALDN had longer warm ischaemia and hospital stay, outcomes improved as the surgical team advanced along the learning curve. This work demonstrates the feasibility of establishing RALDN in a high-volume United Kingdom center without prior robotic experience, providing a foundation for further integration of robotic platforms in kidney transplantation.
Citation	Christou CD, Antoniadis S, Majumder A, Zakri R, Olsburgh J, Callaghan C, Papadakis G, Sran K, Drage M, Decaestecker K, Challacombe B, Kessaris N, Loukopoulos I. Robot-assisted vs hand-assisted laparoscopic donor nephrectomy in the United Kingdom: Equivalent outcomes in the first national series. World J Transplant 2025; In press

Received	2025-08-14 03:13
Peer-Review Started	2025-08-14 03:13
To Make the First Decision
Return for Revision	2025-09-04 07:56
Revised	2025-09-12 10:16
Second Decision	2025-11-26 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-26 11:28
Articles in Press	2025-11-26 11:28
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ISSN	2220-3230 (online)
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