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Articles in Press
12/29/2025 7:29:51 AM | Browse: 16 | Download: 0
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Contemporary adolescent depression: Multidimensional analysis from neurobiological, psychological, and social integrative perspectives
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Li Ma, Xue Fu, Yu Chen and Shui-Xiu Zeng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Rising Stars of Medical Talents “Youth Development Program” |
No. 2023-62 |
| Shanghai Fourth People’s Hospital Research Initiation Special Project |
No. sykyqd06601 |
| Research on Health Policy of Shanghai Municipal Health Commission |
No. 2024HP01 |
| Hongkou District Health Commission Medical Research Project |
No. Hongwei 2401-02 |
| Hongkou District TCM Specialized Diseases/Clinics Construction Project |
No. HKGYQYXM-2026-12 |
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| Corresponding Author |
Shui-Xiu Zeng, Researcher, Department of Pediatrics, Shenzhen People's Hospital, No. 1017 Dongmen North Road, Luohu District, Shenzhen 518020, Guangdong Province, China. zengshuixiu121@163.com |
| Key Words |
Adolescent depression; Multidimensional analysis; Neurobiology; Psychological factors; Social environment; Integrative intervention |
| Core Tip |
This review applies a bio-psycho-social model to comprehensively examine adolescent depression, integrating neurobiological, psychological, and social perspectives. It synthesizes recent evidence on neural circuit dysfunction, hypothalamic-pituitary-adrenal axis dysregulation, cognitive biases, maladaptive emotion regulation, perfectionism, attachment patterns, and environmental risk factors such as social media use and family dysfunction. The article emphasizes the interplay among these domains and highlights the need for personalized, multidimensional prevention and intervention strategies to improve outcomes for adolescents with depression. |
| Citation |
Ma YL, Fu X, Chen Y, Zeng SX. Contemporary adolescent depression: Multidimensional analysis from neurobiological, psychological, and social integrative perspectives. World J Psychiatry 2025; In press |
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Received |
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2025-09-12 08:28 |
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Peer-Review Started |
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2025-09-12 08:28 |
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First Decision by Editorial Office Director |
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2025-10-13 03:11 |
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Return for Revision |
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2025-10-13 03:11 |
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Revised |
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2025-10-21 14:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-29 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-29 07:29 |
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Articles in Press |
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2025-12-29 07:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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