Publication Name	World Journal of Clinical Cases
Manuscript ID	113129
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Elevated body mass index as a prognostic marker in acute liver failure: Implications from a two-decade cohort
Manuscript Source	Invited Manuscript
All Author List	Shree Rath
Funding Agency and Grant Number
Corresponding Author	Shree Rath, MD, Department of Medicine, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India., Sijua, Patrapada, Bhubaneswar 751019, Odisha, India. shreerath4a@gmail.com
Key Words	Body mass index; Acute liver failure; Renal dysfunction; Hepatic encephalopathy; Obesity
Core Tip	The association between elevated body mass index (BMI) and poor outcomes in acute liver failure (ALF) has been underexplored in recent literature. Krishnan et al present a large, two-decade United States cohort showing that overweight and obese patients face a twofold higher risk of death or need for liver transplantation, along with greater prevalence of severe hepatic encephalopathy and renal dysfunction. These findings highlight BMI as an important prognostic marker in ALF and support its integration into risk assessment frameworks. Targeted monitoring and early interventions in this population may help mitigate adverse outcomes.
Citation	Rath S. Elevated body mass index as a prognostic marker in acute liver failure: Implications from a two-decade cohort. World J Clin Cases 2025; In press

Received	2025-08-18 01:55
Peer-Review Started	2025-08-18 01:55
To Make the First Decision
Return for Revision	2025-09-02 06:50
Revised	2025-09-14 12:52
Second Decision	2025-11-20 23:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-21 02:02
Articles in Press	2025-11-21 02:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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