Publication Name	World Journal of Gastroenterology
Manuscript ID	113195
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Predictors of one-year adverse outcomes after laparoscopic resection for hepatocellular carcinoma: Development and validation of an early-warning model
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Feng, Qing-Wang Ye, Qi-Le Wang, Si-Ying Chen, Yao Ma and Fan-Lai Meng
Funding Agency and Grant Number	Funding Agency Grant Number Suqian Science and Technology Program S202317 Medical Research Program of Jiangsu Provincial Health Commission Z2023017 Suqian Talent Elite Program SQCG202409
Corresponding Author	Wei Feng, Chief Physician, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Suqian Hospital of Xuzhou Medical University, No. 138 Huanghe South Road, Suqian 223800, Jiangsu Province, China. fengweisuqian@163.com
Key Words	Primary liver cancer; Minimally invasive resection; Outcomes; Predictors; Least absolute shrinkage and selection operator regression; Prognostic model
Core Tip	Preoperatively assess white blood cell count, alpha-fetoprotein, and liver function; evaluate tumor size and vascular or portal vein invasion through imaging; document cirrhosis status. Apply the least absolute shrinkage and selection operator-based model to calculate individualized 1-year risk and guide tailored postoperative follow-up. High-risk patients should undergo multidisciplinary team review and early intervention. Combine risk score output with albumin-bilirubin scoring to assess hepatic reserve, continuously refining thresholds to enhance accuracy, generalizability, and clinical utility. This integrative approach enables early identification of recurrence risk and supports precision management after minimally invasive resection for hepatocellular carcinoma.
Citation	Feng W, Ye QW, Wang QL, Chen SY, Ma Y, Meng FL. Predictors of one-year adverse outcomes after laparoscopic resection for hepatocellular carcinoma: Development and validation of an early-warning model. World J Gastroenterol 2025; In press

Received	2025-09-12 08:22
Peer-Review Started	2025-09-12 08:23
First Decision by Editorial Office Director	2025-10-13 09:06
Return for Revision	2025-10-13 09:06
Revised	2025-11-07 08:06
Publication Fee Transferred
Second Decision by Editor	2025-12-22 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-22 06:52
Articles in Press	2025-12-22 06:52
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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