Publication Name	World Journal of Hepatology
Manuscript ID	113284
Country	Ukraine

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Metabolically associated fatty liver disease: What hepatologists need to know about this systemic disease
Manuscript Source	Invited Manuscript
All Author List	Alexander Plakida, Olga Iushkovska and Lidia Elżbieta Sierpińska
Funding Agency and Grant Number
Corresponding Author	Alexander Plakida, Full Professor, MD, PhD, Professor, Department of Physical Rehabilitation, Sports Medicine and Physical Training, Odessa National Medical University, Valikhovsky Lane, 2, Odessa 65000, Ukraine. aplakida01@gmail.com
Key Words	Metabolic associated fatty liver disease; Non-alcoholic fatty liver disease; Metabolic dysfunction-associated steatotic liver disease; Metabolic associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis; Diabetes mellitus; Viral hepatitis; Hepatocarcinoma
Core Tip	Metabolically associated fatty liver disease (MAFLD) is the new term replacing non-alcoholic fatty liver disease. Today, it is the most common chronic liver disease worldwide, affecting approximately 38% of the world's population. This comprehensive review offers insight into the various aspects of MAFLD, focusing on terminology, epidemiology, new findings on pathophysiology, key clinical factors, and current treatment options.
Citation	Plakida A, Iushkovska O, Sierpińska LE. Metabolically associated fatty liver disease: What hepatologists need to know about this systemic disease. World J Hepatol 2026; In press

Received	2025-08-21 15:26
Peer-Review Started	2025-08-21 15:26
First Decision by Editorial Office Director	2025-09-03 03:53
Return for Revision	2025-09-03 03:53
Revised	2025-09-23 09:15
Publication Fee Transferred
Second Decision by Editor	2026-01-09 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-09 13:35
Articles in Press	2026-01-09 13:35
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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