Publication Name	World Journal of Clinical Oncology
Manuscript ID	113304
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Post-treatment triglyceride-glucose index as survival protective factors in patients with esophageal squamous cell carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Ling Xiao, Yu-Di Liu, Xue Zhang, Shi-Chuan Zhang and Jia-Hua Lyu
Funding Agency and Grant Number
Corresponding Author	Jia-Hua Lyu, Associate Chief Physician, PhD, Senior Researcher, Department of Radiation Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, No. 55 Section 4, Renmin South Road, Chengdu 610041, Sichuan Province, China. winlttljh@163.com
Key Words	Esophageal squamous cell carcinoma; Chemoradiotherapy; Insulin resistance; Triglyceride-glucose index; Metabolic syndrome
Core Tip	This study shows post-treatment triglyceride-glucose (TyG) index and its derivatives (TyG-body weight, TyG-body mass index) correlate with lower death risk in East Asian esophageal squamous cell carcinoma patients after definitive chemoradiotherapy, outperforming pre-treatment levels (especially in males) and acting as independent prognostic indicators, which may guide prognosis stratification, treatment monitoring, offer novel insights into personalized management, and serve as a robust basis for clinical decision optimization.
Citation	Xiao L, Liu YD, Zhang X, Zhang SC, Lyu JH. Post-treatment triglyceride-glucose index as survival protective factors in patients with esophageal squamous cell carcinoma. World J Clin Oncol 2025; In press

Received	2025-08-22 08:52
Peer-Review Started	2025-08-22 08:52
First Decision by Editorial Office Director	2025-09-03 06:30
Return for Revision	2025-09-03 06:30
Revised	2025-09-16 19:59
Publication Fee Transferred	2025-09-17 15:00
Second Decision by Editor	2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-01 12:10
Articles in Press	2025-12-01 12:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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