Publication Name	World Journal of Methodology
Manuscript ID	113355
Country	Viet Nam

Category	Surgery
Manuscript Type	Minireviews
Article Title	Strengthening trauma care in low- and middle-income countries through guideline adaptation and scalable system reforms
Manuscript Source	Invited Manuscript
All Author List	Kim-Long Le, Tri-Nhan Pham, Minh-Quang Tran, My-Tran Trinh, Phu-Cuong Pham, Quynh-Nhu Duong-Ngoc, Khanh-Phat Thai, Nguyen-Khoi Le, Tuong-Anh Mai-Phan and Hoang-Long Luong-Toan
Funding Agency and Grant Number
Corresponding Author	Nguyen-Khoi Le, PhD, Department of Surgery, Faculty of Medicine, Pham Ngoc Thach University of Medicine, 02 Duong Quang Trung Street, Ward 12, District 10, Ho Chi Minh City 07000, Viet Nam. tg_lenguyenkhoi@pnt.edu.vn
Key Words	Guideline implementation barriers; Trauma systems; Low- and middle-income countries; Primary trauma care; Massive transfusion protocol; Damage-control surgery; Polytrauma resuscitation
Core Tip	This narrative review synthesizes updated global guidelines on early polytrauma management and explores practical, scalable strategies for adapting these recommendations to low- and middle-income countries (LMICs). By integrating context-sensitive clinical priorities—such as Circulation-Airway-Breathing (CAB) sequencing in exsanguination, permissive hypotension, balanced transfusion, damage-control surgery, and point-of-care diagnostics—with phased system reforms in training, referral networks, and trauma registries, LMICs can significantly improve survival without requiring wholesale replication of high-income trauma models.
Citation	Le KL, Pham TN, Tran MQ, Trinh MT, Pham PC, Duong-Ngoc QN, Thai KP, Le NK, Mai-Phan TA, Luong-Toan HL. Strengthening trauma care in low- and middle-income countries through guideline adaptation and scalable system reforms. World J Methodol 2025; In press

Received	2025-08-25 11:04
Peer-Review Started	2025-08-25 11:04
First Decision by Editorial Office Director	2025-09-09 10:02
Return for Revision	2025-09-09 10:02
Revised	2025-09-21 15:15
Publication Fee Transferred
Second Decision by Editor	2025-12-18 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-18 08:04
Articles in Press	2025-12-18 08:04
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com